Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 10/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705006 | 1.00 | PNMT (0.38) | PNMTADRA2AADRA2BADRA2CAAK1 | |
| SCHEMBL27942623 | 0.77 | SRD5A1 (0.38) | — | |
| SCHEMBL27696936 | 0.77 | SRD5A1 (0.38) | — | |
| SCHEMBL27617880 | 0.74 | POLB (0.31) | AAK1 | |
| SCHEMBL27771662 | 0.73 | ATM (0.31) | — | |
| SCHEMBL27689519 | 0.72 | PNMT (0.40) | PNMTADRA2AADRA2BADRA2CPRMT5 | |
| SCHEMBL22534289 | 0.72 | ACACB (0.47) | AAK1 | |
| SCHEMBL28033884 | 0.71 | ATM (0.30) | — | |
| SCHEMBL27493732 | 0.70 | THRA (0.39) | — | |
| SCHEMBL23306121 | 0.70 | ITGB3 (0.39) | PNMTADRA2AADRA2BADRA2CMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039900-A | 6-amino(aza)indane compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor | ABBOTT GMBH & CO KG (DE) | 2007-09-19 | — | — | CN | disclosed |