Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696936 | 0.75 | SRD5A1 (0.38) | — | |
| SCHEMBL27942623 | 0.75 | SRD5A1 (0.38) | — | |
| SCHEMBL27705006 | 0.74 | PNMT (0.38) | AAK1 | |
| SCHEMBL27705019 | 0.74 | PNMT (0.38) | AAK1 | |
| SCHEMBL8402502 | 0.73 | ADRA2A (0.40) | POLBMEN1KMT2ABACE1 | |
| SCHEMBL3161721 | 0.70 | GAA (0.45) | BACE1AAK1 | |
| SCHEMBL27617881 | 0.68 | RAB9A (0.34) | POLBMEN1KMT2AAAK1LMNA | |
| SCHEMBL23704899 | 0.68 | SLC6A3 (0.36) | POLBMEN1KMT2A | |
| SCHEMBL8116867 | 0.68 | HTR2A (0.36) | — | |
| SCHEMBL30744061 | 0.67 | RIPK1 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100384824-C | Acetyl 2-hydroxy-1, 3-diaminoalkanes | PHARMACIA & UPJOHN CO LLC (US) | 2008-04-30 | — | — | CN | disclosed |
| CN-1694870-A | Acetyl 2-hydroxy-1, 3-diaminoalkanes | PHARMACIA & UPJOHN CO LLC (US) | 2005-11-09 | — | — | CN | disclosed |