Glyoxylate

Glyoxylate

SCHEMBL27705261

O=CC(=O)O.OCC1CCCCC1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 1/20 0.41
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH4 P08319 1/20 0.40
ADH7 P40394 1/20 0.40
SLC1A3 P43003 3/20 0.38
SLC1A2 P43004 3/20 0.38
SLC1A1 P43005 3/20 0.38
EPHX2 P34913 1/20 0.38
LMNA P02545 1/20 0.37
CYP2D6 P10635 1/20 0.37
ALOX5 P09917 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
HTT P42858 1/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL7565580 0.85 LMNA (0.42) EPHX1HPGDKMT2ASLC1A3SLC1A2
Acrylic Acid SCHEMBL1629243 0.84 LMNA (0.43) EPHX1HPGDKMT2AADH1BADH1C
Acrylic Acid SCHEMBL29775523 0.84 LMNA (0.43) EPHX1HPGDKMT2AADH1BADH1C
Acrylic Acid SCHEMBL5444389 0.84 LMNA (0.43) EPHX1HPGDKMT2AADH1BADH1C
Acrylic Acid SCHEMBL15463622 0.84 LMNA (0.43) EPHX1HPGDKMT2AADH1BADH1C
Acrylic Acid SCHEMBL25345705 0.84 LMNA (0.43) EPHX1HPGDKMT2AADH1BADH1C
Formic Acid SCHEMBL29261764 0.83 ADH1B (0.44) EPHX1HPGDKMT2AADH1BADH1C
Bicarbonate SCHEMBL9536875 0.83 ALOX5 (0.39) EPHX1HPGDKMT2ASLC1A3SLC1A2
Acetic Acid SCHEMBL3477510 0.81 LMNA (0.39) EPHX1HPGDKMT2ASLC1A3SLC1A2
SCHEMBL330190 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101454270-A Process for preparing hydroxy-aromatic resins, hydroxy-aromatic resins and modifications thereof DSM IP ASSETS BV (NL) 2009-06-10 CN claimed
CN-101977951-A Composition comprising a polyol DSM IP ASSETS BV 2011-02-16 CN disclosed
CN-101977983-A Composition comprising a blend of resins DSM IP ASSETS BV 2011-02-16 CN disclosed
CN-101454270-A Process for preparing hydroxy-aromatic resins, hydroxy-aromatic resins and modifications thereof DSM IP ASSETS BV (NL) 2009-06-10 CN disclosed
CN-101068841-A Hydroxy-aromatic compound, process for the preparation thereof, and use of the compound DSM IP ASSETS BV (NL) 2007-11-07 CN disclosed