Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29147480 | 0.98 | CA2 (0.50) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL27705382 | 0.92 | CA2 (0.48) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL29147476 | 0.88 | CA2 (0.44) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL29264683 | 0.87 | CA2 (0.43) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL28722541 | 0.86 | LTA4H (0.46) | MEN1GAAKMT2ACA1ACE2 | |
| SCHEMBL28718237 | 0.86 | KMT2A (0.39) | CA2MEN1GAAKMT2ACA1 | |
| SCHEMBL30499378 | 0.85 | ACE2 (0.45) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL5812132 | 0.82 | CA1 (0.52) | CA2CA1ACE2 | |
| SCHEMBL28560543 | 0.82 | CA2 (0.50) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL30475458 | 0.82 | CA2 (0.54) | CA2MAPK1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |