Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990363 | 0.88 | NPC1 (0.69) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL14771799 | 0.87 | NPC1 (0.62) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL28230418 | 0.82 | NPC1 (0.57) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL9781781 | 0.81 | NPC1 (0.61) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL295136 | 0.80 | NPC1 (0.69) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| SCHEMBL27537790 | 0.80 | NPC1 (0.59) | NPC1RAB9AEPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL7608732 | 0.80 | NPC1 (0.59) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL690027 | 0.80 | NPC1 (0.59) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL693305 | 0.79 | NPC1 (0.67) | NPC1RAB9AEPHX2HDAC3NCOR2 | |
| Hydrochloric Acid SCHEMBL28989899 | 0.79 | NPC1 (0.67) | NPC1RAB9AEPHX2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101205203-A | Synthesis of benzyloxy urea | UNIV NANCHANG (CN) | 2008-06-25 | — | — | CN | disclosed |