Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28063043 | 0.98 | NPC1 (0.65) | NPC1RAB9AALDH1A1EPHX2PARP10 | |
| Fluoride SCHEMBL27705811 | 0.98 | NPC1 (0.65) | NPC1RAB9AALDH1A1EPHX2PARP10 | |
| SCHEMBL295136 | 0.85 | NPC1 (0.69) | NPC1RAB9AALDH1A1EPHX2HDAC3 | |
| SCHEMBL1990363 | 0.85 | NPC1 (0.69) | NPC1RAB9AALDH1A1EPHX2HDAC3 | |
| SCHEMBL9788446 | 0.84 | NPC1 (0.58) | NPC1RAB9AALDH1A1PARP10 | |
| SCHEMBL7970706 | 0.84 | NPC1 (0.62) | NPC1RAB9AALDH1A1EPHX2PARP10 | |
| Hydrogen Sulfide SCHEMBL5919025 | 0.83 | NPC1 (0.67) | NPC1RAB9AALDH1A1EPHX2HDAC3 | |
| Hydrochloric Acid SCHEMBL28989899 | 0.83 | NPC1 (0.67) | NPC1RAB9AALDH1A1EPHX2HDAC3 | |
| SCHEMBL7381527 | 0.82 | NPC1 (0.61) | NPC1RAB9AEPHX2PARP10HDAC3 | |
| Hydrochloric Acid SCHEMBL27953900 | 0.82 | NPC1 (0.56) | NPC1RAB9AALDH1A1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099883-A1 | ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2015-04-09 | — | — | US | claimed |
| EP-2837620-A1 | ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2015-02-18 | — | — | EP | claimed |
| CN-104203911-A | aryloxy urea compound and pest control agent | NIPPON SODA CO | 2014-12-10 | — | — | CN | claimed |
| CN-101351444-A | Novel pyrrole derivates with histone deacetylation enzyme inhibition activity | BARSKI NATIONALITY UNIVERSITY (ES) | 2009-01-21 | — | — | CN | claimed |
| CN-101205203-A | Synthesis of benzyloxy urea | UNIV NANCHANG (CN) | 2008-06-25 | — | — | CN | claimed |
| CN-101205204-A | Synthesis of N-benzyl-N-benzyloxy urea | UNIV NANCHANG (CN) | 2008-06-25 | — | — | CN | claimed |
| CN-1090615-C | Nα-2- (4-nitrophenylsulfonyl) ethoxycarbonyl amino acid | HYUNDAI PHARMACEUTICAL INDUSTR (KR) | 2002-09-11 | — | — | CN | claimed |
| CN-1234793-A | N 'alpha'-2-(4-nitrophenylsulfonyl) ethyoxycarbonyl-amino acids | HYUNDAI PHARMACEUTICAL INDUSTR (KR) | 1999-11-10 | — | — | CN | claimed |
| EP-0386487-A1 | Novel N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1990-09-12 | — | — | EP | claimed |
| US-12064239-B2 | Device and methods for detection and monitoring of tuberculosis | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2024-08-20 | — | — | US | disclosed |
| US-20210282678-A1 | DEVICE AND METHODS FOR DETECTION AND MONITORING OF TUBERCULOSIS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2021-09-16 | — | — | US | disclosed |
| EP-3602044-A1 | DEVICE AND METHODS FOR DETECTION AND MONITORING OF TUBERCULOSIS | Technion Research & Development Foundation Limited (IL) | 2020-02-05 | — | — | EP | disclosed |
| EP-2628724-B1 | ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO (JP) | 2018-12-05 | — | — | EP | disclosed |
| US-10117871-B2 | 3-hydroxypyrimidine-2,4-dione-5-carboxamides as potent inhibitors of HIV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-11-06 | — | — | US | disclosed |
| CN-1122133-A | Novel bis-oxadiazolidine derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-05-08 | — | — | CN | disclosed |
| WO-1996003983-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0386487-A1 | Novel N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| US-3966958-A | POLYPHAGIA | SMITHKLINE CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
| US-RE28691-E | Methods and compositions for increasing feed intake of animals using tertiary alcohols | SMITHKLINE CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10117871-B2 | 3-hydroxypyrimidine-2,4-dione-5-carboxamides as potent inhibitors of HIV | DPYD, IMPDH2, TYMP | NPC1 4196/4885RAB9A 3934/4885ALDH1A1 97/4885 |
| US-20150099883-A1 | ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT | L3MBTL4, DDT, CHRM1 | NPC1 3786/4885RAB9A 1425/4885ALDH1A1 2212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.