SCHEMBL295136

SCHEMBL295136

O=C(O)NOCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.69
RAB9A P51151 8/20 0.69
ALDH1A1 P00352 3/20 0.50
EPHX2 P34913 1/20 0.50
HDAC3 O15379 1/20 0.49
NCOR2 Q9Y618 1/20 0.49
MAPK1 P28482 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL5919025 0.98 NPC1 (0.67) NPC1RAB9AALDH1A1EPHX2HDAC3
Hydrochloric Acid SCHEMBL28989899 0.98 NPC1 (0.67) NPC1RAB9AALDH1A1EPHX2HDAC3
Phosphoric Acid SCHEMBL7202878 0.92 RAB9A (0.66) NPC1RAB9AEPHX2
Pyrazine SCHEMBL9234910 0.91 NPC1 (0.59) NPC1RAB9AEPHX2KMT2ATDP1
SCHEMBL1990363 0.87 NPC1 (0.69) NPC1RAB9AALDH1A1EPHX2HDAC3
SCHEMBL693305 0.85 NPC1 (0.67) NPC1RAB9AALDH1A1EPHX2HDAC3
SCHEMBL873416 0.83 NPC1 (0.65) NPC1RAB9AALDH1A1EPHX2HDAC3
SCHEMBL14852000 0.83 NPC1 (0.65) NPC1RAB9AALDH1A1EPHX2HDAC3
SCHEMBL680273 0.83 NPC1 (0.65) NPC1RAB9AALDH1A1EPHX2
SCHEMBL16195828 0.83 RAB9A (0.51) NPC1RAB9AHDAC3NCOR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409535-A1 SOLID FORMS OF 3-((1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)AZETIDIN-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOL-2-YL)-2,2-DIFLUOROPROPAN-1-OL AND PROCESSES FOR PREPARING FUSED TRICYCLIC COMPOUNDS COMPRISING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY, INCLUDING METHODS OF THEIR USE GENENTECH, INC. (US) 2024-12-12 US claimed
US-20240024489-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF INSTITUT PASTEUR (FR) 2024-01-25 US claimed
EP-4247828-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF Institut Pasteur (FR) 2023-09-27 EP claimed
CN-116601163-A Protected disaccharides, methods for their preparation, their use in the synthesis of zwitterionic oligosaccharides and conjugates thereof 巴斯德研究所 2023-08-15 CN claimed
CN-111655791-B Pest and ice phobic compositions with fluid additives HRL实验室有限责任公司 2022-11-04 CN claimed
WO-2022106703-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF INSTITUT PASTEUR (FR) 2022-05-27 WO claimed
US-11084794-B2 Controlled cyclization of peptoids to form chiral diketopiperazines TRIAD NATIONAL SECURITY, LLC (US) 2021-08-10 US claimed
US-11072713-B2 Bugphobic and icephobic compositions with fluid additives HRL LABORATORIES, LLC (US) 2021-07-27 US claimed
EP-3746509-A1 BUGPHOBIC AND ICEPHOBIC COMPOSITIONS WITH FLUID ADDITIVES HRL Laboratories, LLC (US) 2020-12-09 EP claimed
CN-111655791-A Pest and ice phobic compositions with fluid additives HRL实验室有限责任公司 2020-09-11 CN claimed
WO-2016043661-A1 MODIFIED PEPTIDE NUCLEIC ACIDS AND THEIR USE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-03-24 WO claimed
WO-2015092739-A1 PROCESS FOR PREPARATION OF ALOGLIPTIN Mylan Laboratories Ltd. (IN) 2015-06-25 WO claimed
CN-101454333-B Lactosamine derivatives GLYCOM AS 2013-08-28 CN claimed
US-8207328-B2 Lactosamine derivatives GLYCOM APS (DK) 2012-06-26 US claimed
EP-1996602-B8 NOVEL LACTOSAMINE DERIVATIVES GLYCOM AS (DK) 2012-03-14 EP claimed
EP-1996602-B1 NOVEL LACTOSAMINE DERIVATIVES GLYCOM APS (DK) 2011-02-16 EP claimed
US-20090234111-A1 Novel Lactosamine Derivatives GLYCOM APS (DK) 2009-09-17 US claimed
CN-101454333-A Novel lactosamine derivatives GLYCOM APS (DK) 2009-06-10 CN claimed
EP-1996602-A1 NOVEL LACTOSAMINE DERIVATIVES Glycom APS (DK) 2008-12-03 EP claimed
WO-2007104311-A1 NOVEL LACTOSAMINE DERIVATIVES GLYCOM APS (DK) 2007-09-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240024489-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF SI, DAD1, FUT5 NPC1 3429/4885RAB9A 2007/4885ALDH1A1 3593/4885
US-11072713-B2 Bugphobic and icephobic compositions with fluid additives FUS, IGF2BP1, IGF2BP3 NPC1 1203/4885RAB9A 3929/4885ALDH1A1 3660/4885
US-20090234111-A1 Novel Lactosamine Derivatives B3GNT2, FUT6, FUT5 NPC1 3320/4885RAB9A 2753/4885ALDH1A1 1300/4885
US-11084794-B2 Controlled cyclization of peptoids to form chiral diketopiperazines NPPA, NPEPPS, RRP15 NPC1 1136/4885RAB9A 3975/4885ALDH1A1 4849/4885
US-20240409535-A1 SOLID FORMS OF 3-((1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)AZETIDIN-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOL-2-YL)-2,2-DIFLUOROPROPAN-1-OL AND PROCESSES FOR PREPARING FUSED TRICYCLIC COMPOUNDS COMPRISING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY, INCLUDING METHODS OF THEIR USE TP53, DPYD, FLI1 NPC1 1976/4885RAB9A 1660/4885ALDH1A1 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.