Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MARS1 | P56192 | 3/20 | 0.53 |
| ▸ | PRCP | P42785 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27687135 | 0.88 | MARS1 (0.65) | GRNSORT1LMNAMARS1TP53 | |
| SCHEMBL27694051 | 0.88 | LMNA (0.53) | GRNSORT1LMNAMARS1PRCP | |
| SCHEMBL4689445 | 0.84 | GRN (0.66) | GRNSORT1LMNATP53MDM2 | |
| SCHEMBL24035609 | 0.80 | LMNA (0.69) | LMNAPRCPTP53CYP1A2CYP2C9 | |
| SCHEMBL27687138 | 0.79 | SMN1; SMN2 (0.69) | GRNSORT1LMNAMARS1TP53 | |
| SCHEMBL28760198 | 0.77 | MARS1 (0.48) | LMNAMARS1TP53MDM2MAPT | |
| SCHEMBL27706390 | 0.76 | MAPT (0.56) | LMNAMARS1TP53MAPTMEN1 | |
| SCHEMBL596066 | 0.75 | SMN1; SMN2 (0.53) | GRNSORT1MARS1TP53MAPT | |
| SCHEMBL2565586 | 0.75 | MAPT (0.56) | GRNSORT1LMNAMARS1TP53 | |
| SCHEMBL8367181 | 0.74 | MARS1 (0.65) | LMNAMARS1TP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101121711-A | Pyrazolcarbazone derivatives and application thereof | UNIV SHANDONG (CN) | 2008-02-13 | — | — | CN | disclosed |
| CN-101085758-A | 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivative, preparation method and application thereof | UNIV SHANDONG (CN) | 2007-12-12 | — | — | CN | disclosed |