Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152590 | 0.97 | ALDH1A1 (0.39) | ALDH1A1KDM4ETDP1PHF8KDM2A | |
| Hydrochloric Acid SCHEMBL3334704 | 0.95 | ALDH1A1 (0.38) | ALDH1A1KDM4ETDP1PHF8KDM2A | |
| Cyclopropane SCHEMBL10359668 | 0.90 | ALDH1A1 (0.35) | ALDH1A1KDM4ETDP1PHF8KDM2A | |
| Acrylamide SCHEMBL28190409 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1 | |
| Ammonia Solution, Strong SCHEMBL27706627 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4ETGFBR1 | |
| SCHEMBL25316068 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1TGFBR1RXFP1 | |
| SCHEMBL3776845 | 0.73 | TGFBR1 (0.35) | ALDH1A1KDM4ETDP1TGFBR1 | |
| Hydrochloric Acid SCHEMBL3866989 | 0.72 | TGFBR1 (0.34) | ALDH1A1KDM4ETGFBR1 | |
| SCHEMBL34095 | 0.70 | TGFBR1 (0.33) | ALDH1A1KDM4ETGFBR1 | |
| SCHEMBL9470604 | 0.70 | TGFBR1 (0.36) | ALDH1A1KDM4ETDP1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124262-B | Composition capable of forming gel containing copolymer and usable copolymer | RHONE POULENC CHIMIE | 2012-04-25 | — | — | CN | disclosed |
| CN-101124262-A | Composition capable of forming a gel comprising a copolymer, and useful copolymers | RHONE POULENC CHIMIE (FR) | 2008-02-13 | — | — | CN | disclosed |