Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776845 | 0.98 | TGFBR1 (0.35) | TGFBR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7945238 | 0.83 | TSHR (0.32) | TGFBR1ALDH1A1KDM4ETSHR | |
| SCHEMBL18040136 | 0.81 | — | — | |
| SCHEMBL34095 | 0.81 | TGFBR1 (0.33) | TGFBR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4102058 | 0.77 | TSHR (0.43) | TSHR | |
| SCHEMBL9470604 | 0.77 | TGFBR1 (0.36) | TGFBR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3334704 | 0.77 | ALDH1A1 (0.38) | TGFBR1ALDH1A1KDM4E | |
| SCHEMBL5461471 | 0.75 | — | — | |
| SCHEMBL6222153 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL2773074 | 0.75 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105097-A1 | Degradable Friction Reducer | SCHLUMBERGER TECHNOLOGY CORPORATION | 2009-04-23 | — | — | US | disclosed |