Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152590 | 0.97 | ALDH1A1 (0.39) | ALDH1A1KDM4ETDP1PHF8KDM2A | |
| Bromide SCHEMBL27706629 | 0.95 | ALDH1A1 (0.38) | ALDH1A1KDM4ETDP1PHF8KDM2A | |
| Cyclopropane SCHEMBL10359668 | 0.90 | ALDH1A1 (0.35) | ALDH1A1KDM4ETDP1PHF8KDM2A | |
| Acrylamide SCHEMBL28190409 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1 | |
| Ammonia Solution, Strong SCHEMBL27706627 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4ETGFBR1 | |
| Hydrochloric Acid SCHEMBL3866989 | 0.77 | TGFBR1 (0.34) | ALDH1A1KDM4ETGFBR1 | |
| SCHEMBL25316068 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1TGFBR1RXFP1 | |
| Hydrochloric Acid SCHEMBL7945238 | 0.73 | TSHR (0.32) | ALDH1A1KDM4ETGFBR1 | |
| SCHEMBL3776845 | 0.73 | TGFBR1 (0.35) | ALDH1A1KDM4ETDP1TGFBR1 | |
| SCHEMBL34095 | 0.70 | TGFBR1 (0.33) | ALDH1A1KDM4ETGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11441106-B2 | Particulate fragrance enhancers | HENKEL AG & CO. KGAA (DE) | 2022-09-13 | — | — | US | claimed |
| CN-112551944-A | Modified bentonite anti-seepage material and preparation method and application thereof | 蒲诃夫 | 2021-03-26 | — | — | CN | claimed |
| CN-111690998-A | Milk protein fiber rich in amino acid animal protein and preparation thereof | 深圳千维生态纺织有限公司 | 2020-09-22 | — | — | CN | claimed |
| EP-3645693-A1 | PARTICULATE FRAGRANCE ENHANCERS | Henkel IP & Holding GmbH (DE) | 2020-05-06 | — | — | EP | claimed |
| WO-2019005578-A1 | PARTICULATE FRAGRANCE ENHANCERS | Henkel IP & Holding GmbH (DE) | 2019-01-03 | — | — | WO | claimed |
| US-20180371378-A1 | PARTICULATE FRAGRANCE ENHANCERS | Henkel IP & Holding GmbH (DE) | 2018-12-27 | — | — | US | claimed |
| CN-101124262-B | Composition capable of forming gel containing copolymer and usable copolymer | RHONE POULENC CHIMIE | 2012-04-25 | — | — | CN | claimed |
| CN-101124262-A | Composition capable of forming a gel comprising a copolymer, and useful copolymers | RHONE POULENC CHIMIE (FR) | 2008-02-13 | — | — | CN | claimed |
| US-5723022-A | Temporary wet strength resins | CYTEC TECHNOLOGY CORP. (US) | 1998-03-03 | — | — | US | claimed |
| US-5128046-A | Chelation, coagulation, water pollution control | NALCO CHEMICAL COMPANY (US) | 1992-07-07 | — | — | US | claimed |
| US-4605702-A | A WATER-SOLUBLE, CATIONIC, ACRYLAMIDE-BASED THERMOSETTING POLYMER MODIFIED BY GLYOXAL; DISPOSABLE PAPER PRODUCTS | AMERICAN CYANAMID COMPANY (US) | 1986-08-12 | — | — | US | claimed |
| EP-4317012-A1 | WATER-SOLUBLE FILM, MEDICINE PACKAGE USING SAME, METHOD FOR PRODUCING SAID WATER-SOLUBLE FILM, AND METHOD FOR PRODUCING SAID MEDICINE PACKAGE | Mitsubishi Chemical Corporation (JP) | 2024-02-07 | — | — | EP | disclosed |
| US-20240002616-A1 | WATER-SOLUBLE FILM, CHEMICAL AGENT PACKAGE USING THE WATER-SOLUBLE FILM, AND PRODUCTION METHODS FOR THE WATER-SOLUBLE FILM AND THE CHEMICAL AGENT PACKAGE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-01-04 | — | — | US | disclosed |
| US-11441106-B2 | Particulate fragrance enhancers | HENKEL AG & CO. KGAA (DE) | 2022-09-13 | — | — | US | disclosed |
| CN-112551944-B | Modified bentonite anti-seepage material and preparation method and application thereof | 华中科技大学 | 2022-07-22 | — | — | CN | disclosed |
| US-5454955-A | In conjunction with a water soluble cationic polymer coagulant and an anionic polymer flocculant | NALCO CHEMICAL COMPANY (US) | 1995-10-03 | — | — | US | disclosed |
| US-5128046-A | Chelation, coagulation, water pollution control | NALCO CHEMICAL COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| US-4605702-A | A WATER-SOLUBLE, CATIONIC, ACRYLAMIDE-BASED THERMOSETTING POLYMER MODIFIED BY GLYOXAL; DISPOSABLE PAPER PRODUCTS | AMERICAN CYANAMID COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
| US-4421782-A | WEAR RESISTANT FLOORING | ARMSTRONG WORLD INDUSTRIES, INC. (US) | 1983-12-20 | — | — | US | disclosed |
| US-4420499-A | N-VINYL LACTAM AND SURFACTANT SOLUTION CURABLE BY ACTINIC RADIATION | ARMSTRONG WORLD INDUSTRIES, INC. (US) | 1983-12-13 | — | — | US | disclosed |