Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15882382 | 0.78 | L3MBTL1 (0.43) | L3MBTL1TDP1 | |
| SCHEMBL781788 | 0.70 | CA2 (0.48) | — | |
| SCHEMBL29398221 | 0.70 | CA2 (0.48) | — | |
| SCHEMBL4830484 | 0.70 | CA2 (0.48) | — | |
| SCHEMBL15219655 | 0.70 | CA2 (0.48) | — | |
| SCHEMBL29386661 | 0.70 | CA2 (0.48) | — | |
| SCHEMBL5723418 | 0.70 | L3MBTL1 (0.39) | L3MBTL1TDP1 | |
| SCHEMBL10733681 | 0.70 | NFKB1 (0.52) | — | |
| Fluoride SCHEMBL27841384 | 0.69 | CA2 (0.47) | — | |
| SCHEMBL10509049 | 0.69 | L3MBTL1 (0.35) | L3MBTL1TDP1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115734-A | Spiro derivatives as lipoxygenase inhibitors | LILLY CO ELI (US) | 2008-01-30 | — | — | CN | disclosed |