Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957940 | 0.78 | RAPGEF4 (0.65) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22187390 | 0.71 | LMNA (0.82) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6241668 | 0.69 | LMNA (0.65) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9494277 | 0.68 | MEN1 (0.64) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27641819 | 0.68 | L3MBTL1 (0.69) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16585728 | 0.66 | P2RX7 (0.60) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30106106 | 0.66 | P2RX7 (0.60) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5709661 | 0.66 | LMNA (0.61) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2024083 | 0.65 | LMNA (0.59) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22187332 | 0.64 | LMNA (0.65) | LMNAMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101070297-B | 2,2,2-trifluoro-N-(2-arylsulf)-a rylamide derivatives and preparing method | UNIV SHANGHAI | 2010-05-19 | — | — | CN | disclosed |
| CN-101070297-A | 2,2,2-trifluoro-N-(2-arylsulf)-a rylamide derivatives and preparing method | UNIV SHANGHAI (CN) | 2007-11-14 | — | — | CN | disclosed |