SCHEMBL27709221

SCHEMBL27709221

Brc1ccc2sc3ccc(Br)cc3c2c1.O=[Ti]=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPM2A O95278 1/20 0.51
PTPN2 P17706 1/20 0.51
PTPN1 P18031 1/20 0.51
PTPN22 Q9Y2R2 1/20 0.51
CYP2A6 P11509 2/20 0.44
MIF P14174 1/20 0.38
PIM1 P11309 2/20 0.36
DYRK1A Q13627 2/20 0.36
CHEK1 O14757 1/20 0.36
AURKA O14965 1/20 0.36
DAPK3 O43293 1/20 0.36
JAK2 O60674 1/20 0.36
PRKD3 O94806 1/20 0.36
MAP4K4 O95819 1/20 0.36
PAK4 O96013 1/20 0.36
ABL1 P00519 1/20 0.36
NTRK1 P04629 1/20 0.36
CSF1R P07333 1/20 0.36
RET P07949 1/20 0.36
MET P08581 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216673 0.91 EPM2A (0.53) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL28283111 0.90 GPR3 (0.52) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL12811607 0.86 EPM2A (0.50) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL10227300 0.84 EPM2A (0.49) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL5019781 0.82 KDM4E (0.48) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL1993262 0.82 EPM2A (0.47) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL26685 0.80 GPR3 (0.61) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL10227304 0.79 EPM2A (0.45) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL24343675 0.78 EPM2A (0.49) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL20664889 0.78 EPM2A (0.45) EPM2APTPN2PTPN1PTPN22CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101255336-B Electroluminescent spectrum-stable blue fluorene-based polymers as well as preparation method and uses thereof UNIV SOUTH CHINA TECH 2011-04-27 CN disclosed
CN-101255336-A Electroluminescent spectrum-stable blue fluorene-based polymers as well as preparation method and uses thereof UNIV SOUTH CHINA TECH (CN) 2008-09-03 CN disclosed