SCHEMBL216673

SCHEMBL216673

Brc1ccc2sc3ccc(Br)cc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPM2A O95278 1/20 0.53
PTPN2 P17706 1/20 0.53
PTPN1 P18031 1/20 0.53
PTPN22 Q9Y2R2 1/20 0.53
CYP2A6 P11509 3/20 0.45
HSP90AA1 P07900 1/20 0.41
GPR3 P46089 1/20 0.39
IDO1 P14902 1/20 0.38
MIF P14174 1/20 0.38
PIM1 P11309 2/20 0.37
JAK2 O60674 2/20 0.37
CHEK1 O14757 1/20 0.37
AURKA O14965 1/20 0.37
DAPK3 O43293 1/20 0.37
PRKD3 O94806 1/20 0.37
MAP4K4 O95819 1/20 0.37
PAK4 O96013 1/20 0.37
ABL1 P00519 1/20 0.37
NTRK1 P04629 1/20 0.37
CSF1R P07333 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12811607 0.95 EPM2A (0.50) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL10227300 0.93 EPM2A (0.49) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL1993262 0.91 EPM2A (0.47) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL27709221 0.91 EPM2A (0.51) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL26685 0.89 GPR3 (0.61) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL10227304 0.87 EPM2A (0.45) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL24343675 0.87 EPM2A (0.49) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL11709976 0.87 ALDH1A1 (0.48) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL15907505 0.87 EPM2A (0.45) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL20664889 0.87 EPM2A (0.45) EPM2APTPN2PTPN1PTPN22CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 718 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118161983-A Hollow sphere structure conjugated microporous polymer TiO2Preparation method and application of composite membrane material 西北民族大学 2024-06-11 CN claimed
CN-117004385-B Circular polarization luminescence excimer compound organic long afterglow material, preparation method and application 南京邮电大学 2024-03-15 CN claimed
CN-114890980-B Process for preparing ionic thiafluorene derivatives 内蒙古大学 2024-02-13 CN claimed
CN-117304453-A Hollow sphere conjugated microporous polymer material capable of efficiently photocatalytic degradation of organic dye wastewater, and preparation method and application thereof 西北民族大学 2023-12-29 CN claimed
CN-117004385-A Circular polarization luminescence excimer compound organic long afterglow material, preparation method and application 南京邮电大学 2023-11-07 CN claimed
CN-114890984-B Preparation method and application of photosensitizer with aggregation-induced emission characteristic 内蒙古大学 2023-08-29 CN claimed
CN-113461545-B Organic phosphorescence composition, preparation method and application thereof 季华恒烨(佛山)电子材料有限公司 2023-07-18 CN claimed
CN-114890981-A Preparation method of amino-substituted dibenzothiophene sulfoxide derivatives 内蒙古大学 2022-08-12 CN claimed
CN-114890984-A Preparation method and application of photosensitizer with aggregation-induced emission characteristic 内蒙古大学 2022-08-12 CN claimed
CN-114805295-A Method for purifying halogenated dibenzothiophene compound 江苏南大光电材料股份有限公司 2022-07-29 CN claimed
CN-113461545-A Organic phosphorescent composition and preparation method and application thereof 季华恒烨(佛山)电子材料有限公司 2021-10-01 CN claimed
CN-113444519-A Organic phosphorescent composition and preparation method and application thereof 季华恒烨(佛山)电子材料有限公司 2021-09-28 CN claimed
CN-112266380-A Hole transport material and synthetic method thereof 冯俊阳 2021-01-26 CN claimed
CN-104479113-B The electrochromic polymeric compounds of structure centered on dibenzothiophenes or dibenzofurans 江西科技师范大学 2017-08-11 CN claimed
CN-103224486-B S,S-dioxo-dibenzothiophene monomer containing polar substituent groups, water/alcohol soluble polymers thereof, and application thereof UNIV SOUTH CHINA TECH 2015-04-22 CN claimed
CN-104479113-A Electrochromic polymer employing dibenzothiophene or dibenzofuran as a center structure UNIV JIANGXI NORMAL SCI & TECH 2015-04-01 CN claimed
CN-104402929-A Phosphine oxide derivative of dibenzothiophene S, S dioxides and preparation method and application thereof UNIV HEILONGJIANG 2015-03-11 CN claimed
US-6022307-A ANGIOGENESIS INHIBITOR AMERICAN CYANAMID COMPANY (US) 2000-02-08 US claimed
US-12550609-B2 Material for organic electroluminescent device and organic electroluminescent device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2026-02-10 US disclosed
US-3952014-A VIRICIDE RICHARDSON-MERRELL INC. (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12550609-B2 Material for organic electroluminescent device and organic electroluminescent device including the same LEF1, TRMT1L, EML4 EPM2A 600/4885PTPN2 4493/4885PTPN1 4355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.