SCHEMBL277105

SCHEMBL277105

Cc1ccc(S(=O)(=O)OCC2(C)COC2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
STAT3 P40763 1/20 0.39
GAA P10253 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
PKM P14618 1/20 0.38
ALDH1A1 P00352 3/20 0.37
VDR P11473 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
ELANE P08246 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7814512 0.94 KMT2A (0.39) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL2156525 0.89 CYP2D6 (0.42) KMT2ASMN1; SMN2STAT3CYP3A4CYP2C9
SCHEMBL17824227 0.88 CYP3A4 (0.43) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL10015859 0.88 KMT2A (0.39) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL3698657 0.87 CA12 (0.42) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL690833 0.85 STAT3 (0.40) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL16641783 0.85 KMT2A (0.49) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL19106783 0.84 CA12 (0.41) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL10171744 0.84 CYP3A4 (0.48) KMT2ASMN1; SMN2STAT3GAACA12
SCHEMBL20898576 0.83 STAT3 (0.41) KMT2ASMN1; SMN2STAT3GAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114075155-B Bisphenol A derivative, preparation method thereof and application thereof in lithography 中国科学院化学研究所 2023-08-01 CN claimed
US-20220373885-A1 BISPHENOL A DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN PHOTOLITHOGRAPHY INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2022-11-24 US claimed
CN-114075155-A Bisphenol A derivative, preparation method thereof and application thereof in photoetching 中国科学院化学研究所 2022-02-22 CN claimed
EP-4251620-B1 AMINO QUINAZOLINE DERIVATIVES AS P2X3 INHIBITORS CHIESI FARM SPA (IT) 2025-04-16 EP disclosed
EP-4536356-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS Xenon Pharmaceuticals Inc. (CA) 2025-04-16 EP disclosed
EP-4522618-A1 TETRAHYDROPYRIDO[3,4-D]PYRIMIDINES COMPOUNDS AS HPK1 INHIBITORS Merck Patent GmbH (DE) 2025-03-19 EP disclosed
US-20240174656-A1 FUSED RING AROMATIC HYDROCARBON DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN LITHOGRAPHY INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2024-05-30 US disclosed
CN-118047739-A Polycyclic aromatic hydrocarbon derivative, preparation method thereof and application thereof in photoetching 中国科学院化学研究所 2024-05-17 CN disclosed
US-20240101531-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS XENON PHARMACEUTICALS INC. (CA) 2024-03-28 US disclosed
US-20240093027-A1 POLYMERS USEFUL AS SURFACE LEVELING AGENTS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-03-21 US disclosed
US-20240025922-A1 TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS MERCK HEALTHCARE KGAA (DE) 2024-01-25 US disclosed
US-5663289-A BINDERS AEROJET-GENERAL CORPORATION (US) 1997-09-02 US disclosed
US-5654450-A THERMOPLASTIC RESIN INTERMEDIATES; TEAR STRENGTH, ADHESION AEROJET-GENERAL CORPORATION (US) 1997-08-05 US disclosed
US-5650483-A PREPARING A SOLUTION OF A CATALYST, AN INITIATOR AND A SOLVENT, CONTACTING SOLUTION WITH A SECOND SOLUTION CONTAINING FLUORINATED OXETANE MONOMER(S) AND CONTROLLING THE TEMPERATURE OF THE MIXTURE AEROJET-GENERAL CORPORATION (US) 1997-07-22 US disclosed
US-5637772-A OIL REPELLENT COATINGS; ANTIFOULING AGENTS; RELEASE AGENTS; ENCAPSULATION OF ELECTRICAL DEVICES; CURING AGENT FOR EPOXIDES AEROJET GENERAL CORPORATION (US) 1997-06-10 US disclosed
WO-1996021657-A1 MONO-SUBSTITUTED FLUORINATED OXETANE MONOMERS AEROJET-GENERAL CORPORATION (US) 1996-07-18 WO disclosed
US-5362848-A Preparation and polymerization of initiators containing multiple oxetane rings: new routes to star polymers AEROJET-GENERAL CORPORATION (US) 1994-11-08 US disclosed
US-4865641-A Herbicidal new thiazolyl ether and thioether derivatives BAYER AKTIENGESELLSCHAFT (DE) 1989-09-12 US disclosed
EP-0281907-A1 Thiazolyl ether and thioether derivatives BAYER AG (DE) 1988-09-14 EP disclosed
EP-0273242-A2 2-Pyri(mi)dylthio-aryl ether BAYER AG (DE) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220373885-A1 BISPHENOL A DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF IN PHOTOLITHOGRAPHY WASF2, BCL2L11, PCNA KMT2A 1796/4885SMN1; SMN2 4860/4885STAT3 3132/4885
US-20240174656-A1 FUSED RING AROMATIC HYDROCARBON DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN LITHOGRAPHY WASF2, FZD7, TCF7L2 KMT2A 1823/4885SMN1; SMN2 4885/4885STAT3 4026/4885
US-20240101531-A1 PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS KCNA1, KCNB1, KCNB2 KMT2A 692/4885SMN1; SMN2 1030/4885STAT3 4550/4885
US-20240025922-A1 TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS PDXK, DTYMK, HIPK1 KMT2A 2685/4885SMN1; SMN2 3927/4885STAT3 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.