Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27940758 | 0.83 | PARP1 (0.46) | TSHRALDH1A1KMT2ALMNACDC7 | |
| SCHEMBL27940770 | 0.82 | TSHR (0.58) | TSHRALDH1A1KMT2ALMNACDC7 | |
| SCHEMBL27922031 | 0.79 | PARP1 (0.57) | TSHRALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27710606 | 0.77 | HSD17B1 (0.42) | TSHRALDH1A1LMNACDC7MAPT | |
| SCHEMBL27710553 | 0.77 | AURKA (0.44) | ALDH1A1KMT2ALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL27710534 | 0.77 | PARP1 (0.41) | TSHRALDH1A1KMT2ALMNACDC7 | |
| SCHEMBL27710515 | 0.76 | DGAT1 (0.45) | ALDH1A1LMNASMN1; SMN2CDC7PARP1 | |
| SCHEMBL29655102 | 0.75 | PGR (0.40) | TSHRALDH1A1KMT2ALMNACYP3A4 | |
| SCHEMBL27730961 | 0.75 | ALDH1A1 (0.44) | TSHRALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27940776 | 0.75 | PARP1 (0.53) | LMNACDC7PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101186586-A | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-28 | — | — | CN | claimed |
| CN-101186586-B | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY | 2010-06-30 | — | — | CN | disclosed |
| CN-101186586-A | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-28 | — | — | CN | disclosed |