Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14020878 | 0.84 | HRH1 (0.65) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL1385530 | 0.74 | KEAP1 (0.55) | HRH1KCNH2NPSR1 | |
| SCHEMBL55533 | 0.72 | HRH1 (0.67) | HRH1KCNH2 | |
| SCHEMBL14232133 | 0.72 | HRH1 (0.42) | HRH1KCNH2HTTNPSR1 | |
| SCHEMBL14029031 | 0.72 | KCNA3 (0.46) | HRH1 | |
| SCHEMBL2619541 | 0.72 | KCNH2 (0.45) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL14125429 | 0.72 | KCNH2 (0.45) | HRH1KCNH2HTTRECQLNPSR1 | |
| SCHEMBL2619538 | 0.72 | KCNA3 (0.46) | HRH1 | |
| SCHEMBL14125383 | 0.72 | KCNA3 (0.46) | HRH1 | |
| Bromide SCHEMBL14892044 | 0.71 | KCNH2 (0.44) | HRH1KCNH2HTTRECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101081846-A | Quinazoline derivative and preparation method and usage thereof | WUWEI MEDICINE TECHNOLOGY SHAN (CN) | 2007-12-05 | — | — | CN | claimed |
| CN-101081846-A | Quinazoline derivative and preparation method and usage thereof | WUWEI MEDICINE TECHNOLOGY SHAN (CN) | 2007-12-05 | — | — | CN | disclosed |