Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809584 | 0.94 | HTR1A (0.40) | HTR1AKMT2ANPC1RAB9AGAA | |
| SCHEMBL27809585 | 0.86 | KMT2A (0.39) | TDP1HTR1AKMT2ANPC1RAB9A | |
| SCHEMBL27787635 | 0.83 | L3MBTL1 (0.43) | KMT2ANPC1RAB9AGAALMNA | |
| SCHEMBL27712950 | 0.78 | KMT2A (0.50) | TDP1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL28784460 | 0.74 | SMN1; SMN2 (0.36) | TDP1KMT2ANPC1RAB9AGAA | |
| SCHEMBL27712868 | 0.70 | KMT2A (0.56) | TDP1KMT2ANPC1RAB9AGAA | |
| SCHEMBL3556218 | 0.69 | MAPT (0.56) | TDP1KMT2AGAALMNAMEN1 | |
| SCHEMBL20993061 | 0.68 | SLC6A2 (0.40) | TDP1HTR1AKMT2AGAALMNA | |
| SCHEMBL27671499 | 0.67 | MAPT (0.44) | KMT2AGAALMNAMEN1SMN1; SMN2 | |
| SCHEMBL6896374 | 0.67 | TSHR (0.53) | KMT2ANPC1RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101805326-A | 1,3-diaryl-3-aromatic amino-1-propanol compound and preparation method and application thereof | UNIV SICHUAN | 2010-08-18 | — | — | CN | claimed |
| CN-101805326-A | 1,3-diaryl-3-aromatic amino-1-propanol compound and preparation method and application thereof | UNIV SICHUAN | 2010-08-18 | — | — | CN | disclosed |