Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.52 |
| ▸ | TUBB | P07437 | 4/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.52 |
| ▸ | IKBKB | O14920 | 5/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728244 | 0.86 | IKBKB (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27712944 | 0.85 | MAPT (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5432647 | 0.73 | MAPT (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27713217 | 0.73 | IKBKB (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5727951 | 0.72 | IKBKB (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1428039 | 0.72 | IKBKB (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4680572 | 0.72 | IKBKB (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27789075 | 0.71 | ALDH1A1 (0.45) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5728563 | 0.71 | MAPT (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7054417 | 0.71 | TUBB4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094845-A | Substituted thiophenes | AICURIS GMBH & CO KG (DE) | 2007-12-26 | — | — | CN | disclosed |