Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | IKBKB | O14920 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728563 | 0.85 | MAPT (0.61) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL27712969 | 0.85 | TUBB4A (0.52) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL5728267 | 0.81 | ALDH1A1 (0.64) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL5728481 | 0.81 | MAPT (0.50) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL9671338 | 0.76 | MAPT (0.43) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL3792914 | 0.76 | ADORA3 (0.54) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL15960089 | 0.76 | GAA (0.75) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL9671119 | 0.75 | BACE1 (0.54) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL27859886 | 0.74 | GAA (0.50) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL28813367 | 0.74 | KDM4E (0.40) | MAPTALDH1A1HPGDGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958475-B | Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases | F. HOFFMANN-LA ROCHE AG (CH) | 2015-11-25 | — | — | CN | disclosed |
| CN-103958521-A | Pyrimidin-4-one derivatives and their use in the treatment, alleviation or prevention of viral diseases | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |
| CN-103958475-A | Heteroaryl hydroxamic acid derivatives and their use in the treatment, alleviation or prevention of viral diseases | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |
| CN-101094845-A | Substituted thiophenes | AICURIS GMBH & CO KG (DE) | 2007-12-26 | — | — | CN | disclosed |