Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MMP14 | P50281 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507261 | 0.87 | LMNA (0.43) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16493578 | 0.86 | LMNA (0.48) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL16493553 | 0.85 | MAPT (0.53) | LMNAMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL16493548 | 0.84 | ALDH1A1 (0.46) | LMNAMEN1KMT2AALDH1A1ADAMTS4 | |
| SCHEMBL5507721 | 0.84 | ALDH1A1 (0.45) | LMNAMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5508114 | 0.81 | MMP3 (0.42) | ALDH1A1NPC1RAB9A | |
| SCHEMBL4956015 | 0.81 | KDM4E (0.47) | LMNAMEN1KMT2AALDH1A1ADAMTS4 | |
| SCHEMBL4958220 | 0.80 | ADAMTS4 (0.48) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2156829 | 0.80 | KMT2A (0.64) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2155489 | 0.80 | KMT2A (0.64) | LMNAMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | claimed |
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |