Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156511 | 0.92 | ALDH1A1 (0.46) | ALDH1A1DRD4CYP3A4MMP13MMP14 | |
| SCHEMBL2155028 | 0.90 | ALDH1A1 (0.47) | ALDH1A1DRD4CYP3A4MMP13MMP14 | |
| SCHEMBL2155679 | 0.85 | HDAC3 (0.45) | ALDH1A1DRD4POLBMEN1KMT2A | |
| SCHEMBL2155025 | 0.82 | MMP13 (0.57) | ALDH1A1DRD4CYP3A4MMP13MMP14 | |
| SCHEMBL2155418 | 0.79 | KMT2A (0.45) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL16493549 | 0.79 | MAPT (0.47) | ALDH1A1DRD4POLBMAPTCACNA1G | |
| SCHEMBL16493548 | 0.78 | ALDH1A1 (0.46) | ALDH1A1DRD4CYP3A4MMP13MMP14 | |
| SCHEMBL2156466 | 0.78 | HDAC3 (0.45) | ALDH1A1DRD4MMP13MMP14POLB | |
| SCHEMBL27713627 | 0.78 | LMNA (0.45) | ALDH1A1DRD4POLBMEN1KMT2A | |
| SCHEMBL2156162 | 0.77 | TP53 (0.50) | ALDH1A1CYP3A4MMP13MMP14POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101124213-A | Sulfonylamino cyclic derivatives and uses thereof | SERONO LAB (CH) | 2008-02-13 | — | — | CN | disclosed |