Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 13/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6356438 | 0.86 | TSHR (0.43) | NOTUMIDO1SLC9A1NUDT1 | |
| SCHEMBL13735546 | 0.80 | IDO1 (0.33) | IDO1 | |
| SCHEMBL7861029 | 0.77 | NUDT1 (0.49) | PTPN11NOTUMIDO1NUDT1SCN9A | |
| SCHEMBL30389722 | 0.77 | SMN1; SMN2 (0.38) | IKBKBPKM | |
| SCHEMBL3391817 | 0.76 | CDC7 (0.42) | ALDH1A1 | |
| SCHEMBL7462082 | 0.75 | IKBKB (0.50) | IKBKBNOTUMSLC9A1NUDT1 | |
| SCHEMBL8986683 | 0.73 | ALDH1A1 (0.44) | PTPN11IKBKBSLC9A1NUDT1SCN9A | |
| SCHEMBL2591837 | 0.73 | — | — | |
| SCHEMBL954343 | 0.72 | BCAT2 (0.47) | IKBKBALDH1A1L3MBTL1 | |
| SCHEMBL30006384 | 0.72 | PTPN11 (0.50) | PTPN11IKBKBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101062916-A | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | disclosed |