Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2770459 | 0.99 | HTT (0.40) | SMN1; SMN2HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL2769084 | 0.87 | MEN1 (0.41) | SMN1; SMN2HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL2771388 | 0.86 | AOC3 (0.49) | SMN1; SMN2HTTLMNAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2768923 | 0.85 | AOC3 (0.51) | SMN1; SMN2HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL2768320 | 0.83 | INPPL1 (0.43) | SMN1; SMN2LMNAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2769962 | 0.82 | INPPL1 (0.43) | SMN1; SMN2LMNAMAPTL3MBTL1MEN1 | |
| SCHEMBL2769381 | 0.76 | ADRA2A (0.40) | ACHEMAOBNPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL2769608 | 0.75 | ADRA2A (0.39) | ACHEMAOBRAB9AAOC3KMT2A | |
| SCHEMBL5808896 | 0.75 | HTR6 (0.50) | SMN1; SMN2HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL3592904 | 0.75 | HTR6 (0.42) | SMN1; SMN2HTTLMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805177-B9 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-09-15 | — | — | EP | claimed |
| EP-1805177-B1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-04-28 | — | — | EP | claimed |
| EP-1805177-B9 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-09-15 | — | — | EP | disclosed |
| EP-1805177-B1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2010-04-28 | — | — | EP | disclosed |
| EP-1805177-A4 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-07-29 | — | — | EP | disclosed |
| US-7541366-B2 | Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2009-06-02 | — | — | US | disclosed |
| US-20070249658-A1 | Pyrrolo[3,2-C]Pyridine Deriatives and Processes for the Preparation Thereof | YUHAN CORPORATION (KR) | 2007-10-25 | — | — | US | disclosed |
| EP-1805177-A1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006025715-A1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249658-A1 | Pyrrolo[3,2-C]Pyridine Deriatives and Processes for the Preparation Thereof | ATP6AP1, HPD, ATP6V1H | SMN1; SMN2 4292/4885HTT 567/4885LMNA 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.