Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773803 | 0.92 | PDE4A (0.41) | ALDH1A1KDM4EHPGDNPC1CA1 | |
| SCHEMBL2772806 | 0.92 | KDM4E (0.48) | ALDH1A1KDM4EHPGDNPC1CA1 | |
| SCHEMBL2773724 | 0.88 | CYP1A1 (0.46) | ALDH1A1KDM4EHPGDNPC1PDE4A | |
| SCHEMBL2771444 | 0.88 | SMPD1 (0.42) | ALDH1A1KDM4EHPGDNPC1CA1 | |
| SCHEMBL2774638 | 0.88 | TP53 (0.40) | ALDH1A1KDM4EHPGDNPC1CA1 | |
| SCHEMBL2772268 | 0.87 | KMT2A (0.44) | ALDH1A1KDM4EHPGDNPC1CA1 | |
| SCHEMBL2788405 | 0.85 | PDE4A (0.51) | ALDH1A1KDM4EHPGDNPC1PDE4A | |
| SCHEMBL2771320 | 0.85 | PTGES (0.54) | ALDH1A1KDM4EHPGDNPC1CA1 | |
| SCHEMBL2771225 | 0.85 | PTGES (0.54) | KDM4EHPGDPOLBMAOBKMT2A | |
| SCHEMBL2772036 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDNPC1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |