Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771225 | 0.91 | PTGES (0.54) | PTGESMAOBALOX5CYP1A1CYP1B1 | |
| SCHEMBL2772806 | 0.91 | KDM4E (0.48) | PTGESMAOBALOX5POLBTP53 | |
| SCHEMBL2805301 | 0.88 | PTGES (0.41) | PTGESMAOBALOX5PIM1CDK5 | |
| SCHEMBL2787046 | 0.86 | PTGES (0.40) | PTGESALOX5TP53ALDH1A1MEN1 | |
| SCHEMBL2771578 | 0.85 | ALDH1A1 (0.41) | PTGESMAOBALOX5POLBTP53 | |
| SCHEMBL2787871 | 0.85 | PDE4D (0.40) | PTGESMAOBALOX5ALDH1A1MEN1 | |
| SCHEMBL2789925 | 0.85 | PDE4A (0.52) | PTGESMAOBKDM4EALDH1A1MEN1 | |
| SCHEMBL2772036 | 0.84 | ALDH1A1 (0.40) | PTGESMAOBALOX5POLBTP53 | |
| SCHEMBL2771444 | 0.83 | SMPD1 (0.42) | PTGESMAOBALOX5POLBTP53 | |
| SCHEMBL2771247 | 0.83 | PDE4A (0.46) | CYP1A1CDK5CDK5R1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |