SCHEMBL27716630

SCHEMBL27716630

Cc1ccc(C(=O)OBr)c(NC(=O)c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.61
KDM4E B2RXH2 3/20 0.52
MAPK1 P28482 1/20 0.52
HSD17B10 Q99714 1/20 0.52
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
MAPT P10636 2/20 0.51
PKM P14618 1/20 0.51
GRIK1 P39086 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
GFER P55789 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
ALDH1A1 P00352 3/20 0.51
ADORA3 P0DMS8 1/20 0.51
NR1H4 Q96RI1 1/20 0.50
HPGD P15428 2/20 0.49
POLB P06746 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901019 0.85 KCNMA1 (0.59) KCNMA1KDM4EMAPK1HSD17B10MEN1
SCHEMBL676149 0.81 KCNMA1 (0.66) KCNMA1MEN1KMT2AMAPTPKM
SCHEMBL16317646 0.79 KCNMA1 (0.76) KCNMA1MEN1KMT2AMAPTGFER
SCHEMBL29175040 0.78 SMN1; SMN2 (0.66) KCNMA1KDM4EMAPK1MEN1KMT2A
SCHEMBL5310996 0.77 KCNMA1 (0.73) KCNMA1HSD17B10MEN1KMT2AMAPT
SCHEMBL27849440 0.77 AKR1C3 (0.50) MAPK1MAPTPKMNPSR1ALDH1A1
SCHEMBL10873010 0.76 KCNMA1 (1.00) KCNMA1MEN1KMT2AMAPTHPGD
SCHEMBL21771978 0.76 KMT2A (0.67) KCNMA1KDM4EMAPK1HSD17B10MEN1
SCHEMBL2275624 0.76 KDM4E (0.64) KDM4EMAPK1HSD17B10MEN1KMT2A
SCHEMBL528361 0.75 HDAC1 (0.70) KCNMA1KDM4EMAPK1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-B novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-101094829-A Novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2007-12-26 CN disclosed