Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696887 | 0.86 | HPGD (0.47) | MAPTALDH1A1MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL27570719 | 0.84 | ALDH1A1 (0.45) | CES2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1317836 | 0.83 | ABCB1 (0.39) | ABCB1ABCC1MAPTALDH1A1MEN1 | |
| SCHEMBL27615398 | 0.82 | CES2 (0.39) | CES2MAPTALDH1A1KMT2AMAPK1 | |
| SCHEMBL17875619 | 0.80 | CES2 (0.53) | CES2ABCB1ABCC1MAPTALDH1A1 | |
| SCHEMBL27834938 | 0.80 | ATM (0.41) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27700395 | 0.80 | ALDH1A1 (0.44) | MAPTALDH1A1MEN1KMT2APKM | |
| SCHEMBL27696821 | 0.79 | ABCB1 (0.38) | CES2ABCB1MAPTALDH1A1MAPK1 | |
| SCHEMBL28818852 | 0.78 | SIRT6 (0.54) | MAPTALDH1A1MAPK1 | |
| SCHEMBL28043906 | 0.78 | MAPT (0.34) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684554-A | Derivatives of azaindazole or diazaindazole type for treating pain | PF MEDICAMENT | 2015-06-03 | — | — | CN | disclosed |
| CN-103923072-A | Substituted Indazole Derivatives Active As Kinase Inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2014-07-16 | — | — | CN | disclosed |
| CN-101754956-B | Substituted indazole derivatives active as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2014-04-23 | — | — | CN | disclosed |
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| CN-101754956-A | Substituted indazole derivatives active as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2010-06-23 | — | — | CN | disclosed |
| CN-101094829-A | Novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |