Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737509 | 0.78 | CD44 (0.33) | ALDH1A1CD44GAA | |
| SCHEMBL27716582 | 0.73 | TSHR (0.45) | ALDH1A1GAA | |
| SCHEMBL28672997 | 0.70 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL27716615 | 0.69 | TDP1 (0.45) | ALDH1A1GAA | |
| SCHEMBL1172198 | 0.67 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL8335117 | 0.66 | CYP3A4 (0.46) | ALDH1A1CD44GAA | |
| SCHEMBL29434817 | 0.66 | ALDH1A1 (0.46) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL345827 | 0.66 | CYP3A4 (0.50) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27443748 | 0.66 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL2963949 | 0.66 | ALDH1A1 (0.46) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101282945-A | Compositions and methods for inhibiting the JAK pathway | RIGEL PHARMACEUTICALS INC (US) | 2008-10-08 | — | — | CN | disclosed |