Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 12/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.39 |
| ▸ | DRD2 | P14416 | 8/20 | 0.39 |
| ▸ | DRD4 | P21917 | 8/20 | 0.39 |
| ▸ | DRD3 | P35462 | 8/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97527 | 0.90 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL5250258 | 0.85 | DRD2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL5250261 | 0.84 | DRD2 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL95580 | 0.74 | POLB (0.50) | — | |
| SCHEMBL96646 | 0.72 | CHRM1 (0.69) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1663701 | 0.69 | CSF1R (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7484378 | 0.68 | CHRM4 (0.37) | CHRM4DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL13606955 | 0.67 | CHRM1 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1663082 | 0.67 | PTPN1 (0.51) | ADRA1DADRA1AADRA1B | |
| SCHEMBL96096 | 0.66 | FAAH (0.43) | CHRM5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101068810-B | Carbostyril compound | OTSUKA PHARMA CO LTD | 2011-02-09 | — | — | CN | disclosed |
| CN-101068810-A | Carbostyril compound | OTSUKA PHARMA CO LTD (JP) | 2007-11-07 | — | — | CN | disclosed |