Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2750910 | 0.82 | CYP11B2 (0.36) | IDO1CLK4CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL18890284 | 0.79 | IDO1 (0.56) | IDO1CLK4GABRG2GABRB3GABRA5 | |
| SCHEMBL5323457 | 0.79 | CYP11B2 (0.55) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL2154026 | 0.78 | CLK4 (0.65) | IDO1CLK4GABRG2GABRB3GABRA5 | |
| SCHEMBL13537172 | 0.77 | CYP11B2 (0.71) | IDO1CLK4GABRG2GABRB3GABRA5 | |
| SCHEMBL29809001 | 0.77 | CYP11B2 (0.71) | IDO1CLK4GABRG2GABRB3GABRA5 | |
| SCHEMBL3721866 | 0.76 | HSD17B1 (0.50) | CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL1201514 | 0.76 | CYP11B2 (0.45) | IDO1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28800800 | 0.76 | IDO1 (0.45) | IDO1NOTUMMAOB | |
| SCHEMBL27787243 | 0.75 | CLK4 (0.63) | IDO1CLK4GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-B | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2015-03-11 | — | — | CN | claimed |
| CN-103068797-B | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2015-03-11 | — | — | CN | disclosed |
| CN-103068797-A | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2013-04-24 | — | — | CN | disclosed |
| CN-101146817-B | Novel compounds derived from 5-thioxylose and therapeutic use thereof | FOURNIER LAB SA | 2011-08-17 | — | — | CN | disclosed |
| CN-101146817-A | Novel compounds derived from 5-thioxylose and therapeutic use thereof | FOURNIER LAB SA (FR) | 2008-03-19 | — | — | CN | disclosed |