Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 4/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671259 | 0.81 | DRD2 (0.57) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL8043067 | 0.79 | TAAR1 (0.55) | TAAR1 | |
| SCHEMBL216654 | 0.78 | DRD2 (0.67) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL29473925 | 0.78 | DRD2 (0.67) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL27427311 | 0.78 | TAAR1 (0.53) | DRD2TAAR1 | |
| SCHEMBL27499784 | 0.78 | DRD2 (0.53) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL27539823 | 0.78 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL27427316 | 0.78 | TAAR1 (0.53) | TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL723832 | 0.77 | DRD2 (0.74) | DRD2DRD1TAAR1CHRM2CHRM1 | |
| SCHEMBL1161892 | 0.77 | OPRK1 (0.62) | DRD2DRD1TAAR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309909-A | 2-phenylethylamino derivatives as calcium and/or sodium channel modulators | NEWRON PHARM SPA (IT) | 2008-11-19 | — | — | CN | disclosed |