Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772069 | 0.85 | HCAR3 (1.00) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL30503507 | 0.84 | HCAR3 (0.74) | HCAR3KDM4EGLAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL18339287 | 0.84 | HCAR3 (0.97) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL11698331 | 0.83 | HCAR3 (0.76) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL1110902 | 0.81 | HCAR3 (0.70) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL10692442 | 0.80 | KDM4E (0.76) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL4299481 | 0.79 | HCAR3 (0.68) | HCAR3KDM4EGLAALDH1A1MAPT | |
| SCHEMBL29492133 | 0.79 | CASP6 (0.69) | HCAR3ALDH1A1LMNATSHRVCAM1 | |
| SCHEMBL1966463 | 0.79 | CASP6 (0.69) | HCAR3ALDH1A1LMNATSHRVCAM1 | |
| SCHEMBL4435755 | 0.79 | HCAR3 (0.67) | HCAR3KDM4EGLAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052444-A | DIAZO COUPLERS FOR MONOAZO DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |