Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363795 | 0.88 | CA2 (0.44) | RELACA2FAAH | |
| SCHEMBL6470707 | 0.88 | CA2 (0.44) | RELACA2FAAH | |
| SCHEMBL28762602 | 0.88 | CA2 (0.44) | RELACA2FAAH | |
| SCHEMBL333178 | 0.88 | CA2 (0.44) | RELACA2FAAH | |
| SCHEMBL1347954 | 0.87 | RELA (0.41) | RELACA2FAAH | |
| Benzene SCHEMBL27582507 | 0.83 | PTPN1 (0.47) | RELAPTPN1 | |
| Carbamic Acid SCHEMBL10399044 | 0.83 | PTPN1 (0.40) | RELACA2PTPN1FAAH | |
| SCHEMBL8827496 | 0.81 | ALDH1A1 (0.35) | RELAALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL4668386 | 0.72 | FAAH (0.45) | PTPN1FAAH | |
| SCHEMBL13671233 | 0.72 | FAAH (0.45) | PTPN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101153039-B | 13, 13a- dihydro berberine derivant and pharmaceutical composition | SHANGHAI INST MATERIA MEDICA | 2010-12-01 | — | — | CN | disclosed |
| CN-101153039-A | 13, 13a- dihydro berberine derivant, pharmaceutical composition and uses of the same | SHANGHAI DRUG INST CHINESE ACA (CN) | 2008-04-02 | — | — | CN | disclosed |