Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769438 | 0.87 | MEN1 (0.34) | MEN1KMT2ANPSR1 | |
| SCHEMBL8862832 | 0.83 | ICMT (0.30) | ICMT | |
| SCHEMBL21480360 | 0.81 | — | — | |
| SCHEMBL31377502 | 0.80 | TP53 (0.30) | POLB | |
| SCHEMBL15514367 | 0.80 | TP53 (0.30) | POLB | |
| SCHEMBL31124412 | 0.80 | TP53 (0.30) | POLB | |
| SCHEMBL31748685 | 0.80 | TP53 (0.30) | POLB | |
| SCHEMBL16469637 | 0.80 | TP53 (0.30) | POLB | |
| SCHEMBL1144654 | 0.80 | TP53 (0.30) | POLB | |
| SCHEMBL2773423 | 0.76 | OPRM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965260-B1 | Imaging member comprising asymmetric arylamine compounds and processes for making these compounds | XEROX CORP (US) | 2010-04-21 | — | — | EP | disclosed |
| EP-1965260-A1 | Asymmetric arylamine compounds and processes for making the same | Xerox Corporation (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20080206662-A1 | Asymmetric arylamine compounds and processes for making the same | XEROX CORPORATION (US) | 2008-08-28 | — | — | US | disclosed |