SCHEMBL2769438

SCHEMBL2769438

Cc1ccc(N(c2ccc(C3=CCC(Cl)(c4ccccc4)C=C3)cc2)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772216 0.87 HTT (0.33) MEN1KMT2ANPSR1
SCHEMBL8083541 0.76 S1PR1 (0.34)
SCHEMBL6562524 0.75 CYP1A2 (0.39) MEN1KMT2A
SCHEMBL2770517 0.72
SCHEMBL2773423 0.72 OPRM1 (0.30)
SCHEMBL29755820 0.71 KDM4E (0.37)
SCHEMBL5422875 0.71 ALDH1A1 (0.39) MEN1KMT2A
SCHEMBL17735816 0.71 ALDH1A1 (0.39) MEN1KMT2A
SCHEMBL20671322 0.71 ALDH1A1 (0.43) MEN1KMT2ANPSR1
SCHEMBL13136838 0.71 ALDH1A1 (0.39) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1965260-B1 Imaging member comprising asymmetric arylamine compounds and processes for making these compounds XEROX CORP (US) 2010-04-21 EP disclosed
EP-1965260-A1 Asymmetric arylamine compounds and processes for making the same Xerox Corporation (US) 2008-09-03 EP disclosed
US-20080206662-A1 Asymmetric arylamine compounds and processes for making the same XEROX CORPORATION (US) 2008-08-28 US disclosed