SCHEMBL2773423

SCHEMBL2773423

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C3=CCC(Br)(c4ccccc4)C=C3)cc2)cc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.30
OPRK1 P41145 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2769350 0.92 KDM4E (0.33)
SCHEMBL2772181 0.83 HSD11B1 (0.36) OPRM1OPRL1
SCHEMBL11819984 0.82
SCHEMBL5918725 0.81
SCHEMBL6563901 0.79 ALDH1A1 (0.38)
SCHEMBL19289340 0.77 APP (0.33)
SCHEMBL2772216 0.76 HTT (0.33)
SCHEMBL2770135 0.75 CYP2C19 (0.31)
SCHEMBL29755820 0.74 KDM4E (0.37)
SCHEMBL5551882 0.74 CYP2C19 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1965260-B1 Imaging member comprising asymmetric arylamine compounds and processes for making these compounds XEROX CORP (US) 2010-04-21 EP disclosed
EP-1965260-A1 Asymmetric arylamine compounds and processes for making the same Xerox Corporation (US) 2008-09-03 EP disclosed
US-20080206662-A1 Asymmetric arylamine compounds and processes for making the same XEROX CORPORATION (US) 2008-08-28 US disclosed