Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722329 | 0.87 | KDM4E (0.38) | HDAC1ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL27722215 | 0.81 | PABPC1 (0.34) | HDAC1ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL27722258 | 0.80 | HDAC1 (0.33) | HDAC1 | |
| SCHEMBL28772943 | 0.79 | ATP4A (0.50) | HDAC6MEN1KMT2A | |
| SCHEMBL27722200 | 0.79 | HDAC1 (0.41) | TSPOHDAC1GPR139 | |
| SCHEMBL27701758 | 0.77 | PLAU (0.40) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL27722214 | 0.75 | HDAC1 (0.39) | HDAC1GAA | |
| SCHEMBL27722221 | 0.73 | HDAC1 (0.35) | HDAC1 | |
| SCHEMBL27722223 | 0.71 | GAA (0.49) | HDAC1ALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL27701769 | 0.71 | KDM4E (0.41) | HDAC1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |