Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771247 | 0.93 | PDE4A (0.46) | KDM4EALDH1A1USP2LMNATSHR | |
| SCHEMBL2773724 | 0.89 | CYP1A1 (0.46) | KDM4EALDH1A1USP2LMNATSHR | |
| SCHEMBL2772806 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1LMNAHSD17B10PDE4A | |
| SCHEMBL2773020 | 0.83 | KMT2A (0.43) | KDM4EALDH1A1TSHRHSD17B10NPC1 | |
| SCHEMBL2771444 | 0.83 | SMPD1 (0.42) | KDM4EALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL2785396 | 0.82 | KDM4E (0.42) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2772272 | 0.81 | PDE4A (0.54) | KDM4EALDH1A1USP2LMNATSHR | |
| SCHEMBL2774638 | 0.81 | TP53 (0.40) | KDM4EALDH1A1USP2LMNATSHR | |
| SCHEMBL2771578 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNAHSD17B10PDE4A | |
| SCHEMBL2772268 | 0.80 | KMT2A (0.44) | KDM4EALDH1A1LMNAHSD17B10PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |