Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709307 | 0.91 | RAB9A (0.32) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL28757379 | 0.88 | NPC1 (0.30) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL31121574 | 0.88 | NPC1 (0.30) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8526230 | 0.80 | FFAR1 (0.32) | RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL5014699 | 0.77 | MAPT (0.31) | SMN1; SMN2MAPT | |
| SCHEMBL27633572 | 0.76 | PDK2 (0.33) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL9862294 | 0.76 | KIF11 (0.31) | — | |
| SCHEMBL27602697 | 0.75 | HSD11B1 (0.33) | RAB9ANPC1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL16400085 | 0.74 | KIF11 (0.34) | — | |
| SCHEMBL28536651 | 0.74 | CES1 (0.32) | CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193635-A | Multicyclic compounds and methods of their use | LEXICON GENETICS INC (US) | 2008-06-04 | — | — | CN | claimed |
| CN-101193635-A | Multicyclic compounds and methods of their use | LEXICON GENETICS INC (US) | 2008-06-04 | — | — | CN | disclosed |