Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5479512 | 0.77 | MAPT (0.35) | MAPTSMN1; SMN2 | |
| SCHEMBL8501780 | 0.77 | FFAR1 (0.36) | MAPTSMN1; SMN2 | |
| SCHEMBL27722980 | 0.77 | RAB9A (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL6709307 | 0.77 | RAB9A (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL28745837 | 0.76 | MEN1 (0.33) | — | |
| SCHEMBL8486887 | 0.75 | MAPT (0.33) | MAPTSMN1; SMN2 | |
| SCHEMBL6808145 | 0.75 | MAPT (0.33) | MAPTSMN1; SMN2 | |
| SCHEMBL27604192 | 0.75 | MAPT (0.33) | MAPTSMN1; SMN2 | |
| SCHEMBL31121574 | 0.74 | NPC1 (0.30) | SMN1; SMN2 | |
| SCHEMBL28757379 | 0.74 | NPC1 (0.30) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893562-A1 | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B | Merck Frosst Canada Ltd. (CA) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006133559-A1 | REVERSIBLE INHIBITORS OF MONOAMINE OXIDASE A AND B | MERCK FROSST CANADA LTD. (CA) | 2006-12-21 | — | — | WO | disclosed |