SCHEMBL4224940

SCHEMBL4224940

CC(C)c1ccc(C(C)(C)OOC=CC(=O)OCCOC(=O)O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
POLB P06746 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
KIF11 P52732 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTT P42858 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8761490 0.96 CYP2D6 (0.36) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL8972266 0.90 CYP2D6 (0.33) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL2772376 0.86 MAPK1 (0.43) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL9862022 0.85 LMNA (0.34) CYP2D6CYP2C9HIF1ASMN1; SMN2NPC1
SCHEMBL8853458 0.83 CYP2D6 (0.38) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL9851460 0.80 LMNA (0.37) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL7692322 0.79 HCAR2 (0.35) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL9336311 0.78 NPC1 (0.37) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL9847930 0.77 CYP2D6 (0.35) CYP2D6CYP2C9HIF1AKDM4EMAPK1
SCHEMBL10435073 0.77 MAPK1 (0.42) HIF1AKDM4EMAPK1SMN1; SMN2HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5140083-A Copolymerized with an unsaturated peroxycarbonate or peroxyester; molding materials; materials handling; heat resistance, impact strength; storage stability NIPPON OIL AND FATS CO., LTD. (JP) 1992-08-18 US claimed
CN-107531978-B Methacrylic resin composition 株式会社可乐丽 2020-11-03 CN disclosed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
WO-2009100986-A1 BIOCIDAL COMPOSITIONS FOR PLASTICS BASF SE (DE) 2009-08-20 WO disclosed
US-6476125-B1 Fluorine-containing polymer alloy, and method for its preparation and method for its molding ASAHI GLASS COMPANY LTD. (JP) 2002-11-05 US disclosed
EP-0761757-B1 Fluorine-containing polymer alloy, and method for its preparation and method for its molding ASAHI GLASS CO LTD (JP) 1999-12-01 EP disclosed
US-5965275-A Adhesive fluorine-containing polymer and laminate employing it ASAHI GLASS COMPANY LTD. (JP) 1999-10-12 US disclosed
US-5736610-A Adhesive fluorine-containing polymer and laminate employing it ASAHI GLASS COMPANY LTD. (JP) 1998-04-07 US disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0608856-B1 Graft precursor and process for producing grafted aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1997-07-09 EP disclosed
EP-0381861-A2 Maleimide copolymer and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1990-08-16 EP disclosed
EP-0368295-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1990-05-16 EP disclosed
US-4923956-A Containing free radical polymerizable organic peroxide NIPPON OIL AND FATS CO., LTD. (JP) 1990-05-08 US disclosed
EP-0361400-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-04-04 EP disclosed
US-4879347-A ETHYLENE POLYMER, VINYL MONOMER, RADICAL POLYMERIZABLE ORGANIC PEROXIDE, FREE RADICAL CATALYST, COPOLYMERIZATION NIPPON OIL AND FATS CO., LTD. (JP) 1989-11-07 US disclosed
EP-0338303-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-10-25 EP disclosed
EP-0338544-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-10-25 EP disclosed
EP-0334296-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-09-27 EP disclosed
US-4839432-A USING A UNSATURATED PEROXY FREE RADICAL CATALYSTS NIPPON OIL AND FATS CO., LTD. (JP) 1989-06-13 US disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed