Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | S100A4 | P26447 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723778 | 0.88 | ALDH1A1 (0.36) | ALDH1A1NQO2KDM4EABCG2SMN1; SMN2 | |
| SCHEMBL535887 | 0.84 | TUBB4A (0.40) | COMTALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27799958 | 0.79 | ALDH1A1 (0.36) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27723773 | 0.77 | SIRT6 (0.41) | ALDH1A1KDM4EABCG2SMN1; SMN2GAA | |
| SCHEMBL3633692 | 0.77 | KDM4E (0.36) | COMTALDH1A1KDM4ELCKSMN1; SMN2 | |
| SCHEMBL27723771 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL535545 | 0.72 | TUBB4A (0.40) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL2938117 | 0.71 | TUBB4A (0.42) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL27723811 | 0.71 | KDM4E (0.46) | ALDH1A1KDM4ELCKGAAMAPT | |
| SCHEMBL27778825 | 0.70 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273029-B | Bicyclic bisamide derivatives and their use as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-27 | — | — | CN | disclosed |
| CN-101273029-A | Bicyclic bisamide derivatives and their use as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-24 | — | — | CN | disclosed |