SCHEMBL3633692

SCHEMBL3633692

COC(=O)c1cc(O)c2ccc(C(F)(F)F)nc2c1.COC(=O)c1cc2nc(C(F)(F)F)ccc2c(O)c1[N+](=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
GAA P10253 1/20 0.36
NFKB1 P19838 1/20 0.36
XDH P47989 1/20 0.36
GFER P55789 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
FUT7 Q11130 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL535887 0.92 TUBB4A (0.40) KDM4EL3MBTL1LMNATUBB4ATUBB
SCHEMBL535636 0.85 KDM4E (0.45) KDM4EL3MBTL1LMNAPOLBGAA
SCHEMBL535545 0.81 TUBB4A (0.40) KDM4EL3MBTL1LMNATUBB4ATUBB
SCHEMBL2938117 0.80 TUBB4A (0.42) KDM4EL3MBTL1LMNAPOLBTUBB4A
SCHEMBL27723769 0.77 COMT (0.36) KDM4EL3MBTL1GAAALDH1A1KMT2A
SCHEMBL535642 0.75 SDHB (0.37) KDM4EPOLBGAATUBB4ATUBB
SCHEMBL2934012 0.71 TUBB4A (0.45) KDM4EL3MBTL1LMNATDP1TUBB4A
SCHEMBL2935943 0.70 PKM (0.51) KDM4ELMNAPOLBALDH1A1MAPT
SCHEMBL535729 0.69 IGF1R (0.39) LMNAPOLBALDH1A1KMT2AMAPT
SCHEMBL9945607 0.68 KDM4E (0.53) KDM4EL3MBTL1LMNAGAAXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed