Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794708 | 0.86 | CACNA1G (0.37) | EDNRAMEN1KMT2AATMALDH1A1 | |
| SCHEMBL10856406 | 0.79 | NOTUM (0.43) | MEN1KMT2AATMHDAC4HDAC7 | |
| SCHEMBL15355353 | 0.76 | EDNRA (0.39) | EDNRAEDNRBALDH1A1CES2CES1 | |
| SCHEMBL23611584 | 0.76 | EDNRA (0.39) | EDNRACYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL15355340 | 0.74 | EDNRA (0.38) | EDNRAATMEDNRBALDH1A1CES2 | |
| SCHEMBL10854136 | 0.74 | ALDH1A1 (0.38) | EDNRAMEN1KMT2AATMALDH1A1 | |
| SCHEMBL23611631 | 0.73 | FFAR2 (0.43) | — | |
| SCHEMBL27673616 | 0.71 | KDM4E (0.42) | MEN1KMT2ACYP2C9CYP1A2CYP2D6 | |
| SCHEMBL23611599 | 0.68 | FFAR2 (0.37) | — | |
| SCHEMBL18986768 | 0.67 | ACE (0.48) | CYP2C9CYP1A2CYP2D6CYP2C19CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101312720-A | 2-aminobenzamide derivative | ASTELLAS PHARMA INC (JP) | 2008-11-26 | — | — | CN | disclosed |