SCHEMBL10854136

SCHEMBL10854136

O=C(C(Cl)Cl)N1C(O)c2ccccc2C1O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 2/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ATM Q13315 1/20 0.33
RAB9A P51151 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HPGD P15428 3/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 1/20 0.31
TRPA1 O75762 1/20 0.31
EDNRA P25101 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10858026 0.76 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2HTTGAAKMT2A
SCHEMBL27723939 0.74 EDNRA (0.39) ALDH1A1HTTKMT2AMEN1ATM
SCHEMBL10856406 0.72 NOTUM (0.43) SMN1; SMN2GAAKMT2AMEN1ATM
SCHEMBL10481211 0.69 PRCP (0.44) ALDH1A1KMT2AMEN1
SCHEMBL16794708 0.67 CACNA1G (0.37) ALDH1A1SMN1; SMN2KMT2AMEN1ATM
SCHEMBL2687557 0.66 MAOA (0.37) KMT2AMEN1ATMRAB9A
SCHEMBL9508210 0.64 NOTUM (0.43) ALDH1A1SMN1; SMN2HTTGAA
SCHEMBL27562601 0.63 ALDH1A1 (0.33) ALDH1A1KMT2AMEN1ATMRAB9A
SCHEMBL27762929 0.62 CYP1A2 (0.45) HTTHPGDMAPT
SCHEMBL27673616 0.61 KDM4E (0.42) ALDH1A1KMT2AMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0067714-A2 Phthalaldehyde adduct and image-forming compositions incorporating the same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-12-22 EP claimed
US-4596876-A Isoindoline compounds EASTMAN KODAK COMPANY (US) 1986-06-24 US disclosed
US-4410623-A COBALT (III) COMPLEX WITH AMINE LIGAND EASTMAN KODAK COMPANY (US) 1983-10-18 US disclosed
EP-0067714-A2 Phthalaldehyde adduct and image-forming compositions incorporating the same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-12-22 EP disclosed