Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496065 | 0.88 | ALDH1A1 (0.51) | CA1CA2CA3CA6CA7 | |
| SCHEMBL13451005 | 0.80 | CA1 (0.53) | CA1CA2CA3CA6CA7 | |
| SCHEMBL5113833 | 0.80 | LIPC (0.60) | CA1CA2CA3CA6CA7 | |
| SCHEMBL7181978 | 0.79 | MAPT (0.54) | EPHX2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2424448 | 0.78 | HCAR3 (0.56) | CA1CA2CA3CA6CA7 | |
| SCHEMBL27903406 | 0.76 | PTGDR2 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2426534 | 0.76 | HCAR3 (0.57) | CA1CA2CA3CA6CA7 | |
| SCHEMBL13568755 | 0.76 | ROCK2 (0.62) | CA1CA2CA3CA6CA7 | |
| SCHEMBL13450303 | 0.76 | CA1 (0.48) | CA1CA2CA3CA6CA7 | |
| SCHEMBL14454098 | 0.75 | CFTR (0.50) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101312720-A | 2-aminobenzamide derivative | ASTELLAS PHARMA INC (JP) | 2008-11-26 | — | — | CN | disclosed |