Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 4/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591584 | 0.91 | CNR2 (0.37) | RORCMAPK8MAPK9MAPK10CNR2 | |
| SCHEMBL27724115 | 0.91 | CYP3A4 (0.35) | CYP3A4ALDH1A1F10PRSS1PRSS2 | |
| SCHEMBL27703386 | 0.90 | CYP3A4 (0.38) | CNR2CYP3A4ALDH1A1TP53MAPT | |
| SCHEMBL4592518 | 0.89 | CYP3A4 (0.34) | CNR2CYP3A4F10TP53MAPT | |
| SCHEMBL27703387 | 0.88 | RAB9A (0.39) | CNR2CYP3A4ALDH1A1MAPTEGFR | |
| SCHEMBL27703384 | 0.86 | UTS2R (0.40) | PSMB5RORCTP53MAPTEGFR | |
| SCHEMBL27723969 | 0.84 | ALDH1A1 (0.39) | CYP3A4ALDH1A1GLP1R | |
| SCHEMBL27723968 | 0.82 | EPHX2 (0.37) | CNR2CYP3A4ALDH1A1MAPT | |
| SCHEMBL4592219 | 0.82 | MAPT (0.37) | CNR2CYP3A4ALDH1A1TP53MAPT | |
| SCHEMBL27723970 | 0.82 | TAAR1 (0.36) | CNR2CYP3A4TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189209-A | C5a receptor antagonists | JERINI AG (DE) | 2008-05-28 | — | — | CN | disclosed |