Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 12/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579544 | 0.94 | ADRB2 (0.42) | ADRB2BACE1BCHECTSDCTSB | |
| SCHEMBL28748406 | 0.90 | MEN1 (0.39) | ADRB2BACE1BCHECTSDCTSB | |
| SCHEMBL3351919 | 0.84 | BACE1 (0.46) | BACE1CTSDCTSB | |
| SCHEMBL6647479 | 0.84 | BACE1 (0.46) | BACE1CTSDCTSB | |
| SCHEMBL27593079 | 0.79 | ABL1 (0.37) | BACE1CTSD | |
| SCHEMBL7111374 | 0.76 | HTT (0.52) | BACE1BCHECTSDLMNAALDH1A1 | |
| SCHEMBL5219600 | 0.76 | ANPEP (0.46) | BCHELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27629843 | 0.75 | LMNA (0.63) | LMNAMEN1KMT2A | |
| SCHEMBL27629795 | 0.75 | LMNA (0.43) | BACE1BCHELMNA | |
| SCHEMBL7054663 | 0.74 | DNM1 (0.55) | BACE1BCHECTSDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1447789-A | Compounds for treating alzheimer's disease | ELAN PHARM INC (US) | 2003-10-08 | — | — | CN | claimed |
| CN-100366605-C | Compounds to treat alzheimer's disease | ELAN PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| CN-101090883-A | Substituted hydroxyethylamines | ELAN PHARM INC (US) | 2007-12-19 | — | — | CN | disclosed |
| CN-1447789-A | Compounds for treating alzheimer's disease | ELAN PHARM INC (US) | 2003-10-08 | — | — | CN | disclosed |